In my case I have used ajax calendar. Calendar gets poped up on button and on some textboxes. Sometimes it would respond good but sometime not get poped up.
Sir, I have developed a web Project using VS 2012. I have created VirtualDirectory for application itself.
Whenever application runs from vs the calendar works properly.
Then I have published whole project and manually configured on local IIS , then calendar won't responds on any page and also every button that binded with CalnedarExtender produce PostBack.